Serine is a non essential amino acid. Serine is known to increase the immune system by building up antibodies, aid in the proper metabolism of fats and fatty acids, and assist in the growth of muscles. A storage source of glucose by the liver and muscles; helps strengthen the immune system by providing antibodies; synthesizes fatty acid sheath around nerve fibers. •
Serine is one of the 3 most important glycogenic amino acids, the others being Alanine and Glycine.
Critical in maintaining blood sugar levels.
Boosts immune system by assisting in production of antibodies and immunoglobulins.
Myelin sheath (the fatty acid complex that surrounds the axons of nerves is derived from serine. One variation of Serine namely Phosphotidyl Serine, a minor amino acid serves several important functions within the central nervous system, including development of the myelin sheath. Multiple Sclerosis is one of the so-called "De-myelinating Diseases."
Required for growth and maintenance of muscle.
The amino acid Glycine is a precursor to Serine and the two are inter-convertible.
Phosphatidylserine an essential and critical member of a class of phospholipids (phosphatides) found in all tissues, especially in brain and nerve tissues. Free Serine can be converted into choline via phosphatdylethanolamine with the help of methyl groups from Methionine. Mostly found in the cytoplasmic side of cell membranes and is negatively charged, having a synergistic effect on healing of membranes in the presence of prothrombin and other healing cofactors (Factor Va, Ca2+, Vitamin K) Essential in the formation and maintenance of neural tissue and neural membranes.
Signs or Symptoms of a Deficiency: Total body gamma and neutron irradiation.
Hypoglycemia.
Candidiasis.
Excess maybe seen in: Vitamin B-6 Deficiency
Phosphoserine, a minor amino acid, a modification of Serine, is a good predictor of Vitamin B-6 deficiency, in particular the form of Vitamin B-6 called Pryidoxal-5-Phosphate (P5P). If plasma Phosphoserine levels are abnormally high, that is a clear indication of P5P deficiency. P5P is critical in amino acid processes. Tyrosine, for example, cannot be converted into the neurotransmitter Norepinephrine if there is not enough P5P. Likewise, Tryptophan cannot be converted into the neurotransmitter Serotonin if there is not enough P5P.
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