June 02, 2005 - MILAN, Italy - Pigs given a CLA preparation containing 50-percent CLA isomers exhibited decreased adipocyte size compared to controls. The researchers noted inducible Nitric Oxide (NO) synthase expression was lower in pigs fed CLA, suggesting the antiadipogenic effect of CLA is indirect via downregulation of a NO-mediated lipolytic pathway.
Conjugated linoleic acid (CLA) limited fat formation in pigs by an indirect effect on a key fat degeneration parameter, according to a recent study.
June issue of the Journal of Nutrition (135:1444-50, 2005).
Source: Journal of Nutrition
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