Part of the vitamin B-complex and is a co-factor with the B vitamins.
Choline aids in nerve transmission and utilization of fat and hormone production and in controlling fat & cholesterol buildup in the body. Helps control cholesterol, transferring nerve impulse to the brain, helps against memory loss and senile dementia, aids the liver in eliminating toxins, poisons and drugs from the bloodstream. Helps maintain normal kidney and bladder function. prevents fat from accumulating in the liver; facilitates the movement of fats in the cells; helps regulate the kidneys, liver & gallbladder; important for nerve transmission; helps improve memory. Choline may help in cirrhosis and fatty degeneration of the liver, hardening of the arteries, heart problems, high blood pressure, hemorrhaging kidneys.
Choline is an essential welltrient found in most plants and animals, one of the main components of lecithin in the form of phospholipid lecithin, utilized as a building unit, and is essential in some metabolic processes. Essential functions include: building and maintaining cell membranes, fat metabolism, cholesterol metabolism and preventing abnormal accumulation of fat in the liver, formation of Acetylcholine used in transmethylation reactions (precursors of methylated compounds, i.e. creatine, choline, and adrenaline), and improves brain function and memory retention. Believed to lower cholesterol, soothe nerves, enhance both skin and hair, and may be necessary for storage of Vitamin A. Aids in hormone production and is needed for nerve transmission. Acetylcholine controls eye fluid pressure during the day and may be heplful for glaucoma.
Phosphatidylcholine acts as a supplier of choline, which is needed for cell membrane integrity and to facilitate the movement of fats in and out of cells. It is a component of the neurotransmitter acetylcholine and is needed for normal brain functioning, particularly in infants. Although the human body can synthesize choline, additional amounts from the diet are considered essential under certain circumstances.
History: Choline was discovered over a century ago. Choline can improve health in the areas of brain development, including memory function throughout life, cardiovascular health, improved liver function, and reproductive development.
Choline is a dietary component important for the structural integrity of cell membranes, methyl metabolism, cholinergic neurotransmission, transmembrane signaling, and lipid and cholesterol transport and metabolism. Human cells grown in culture have an absolute requirement for choline (Eagle, 1955). When cells are deprived of choline, they die by apoptosis (Albright et al., 1996; Cui et al., 1996; Holmes-McNary et al., 1997; James et al., 1997; Shin et
Technicals: Choline functions as a precursor for acetylcholine, phospholipids, and the methyl donor betaine. The primary criterion used to estimate the Adequate Intake (AI) for choline is the prevention of liver damage as assessed by measuring serum alanine aminotransferase levels. The AI for adults is 550 mg/day of choline for men and 425 mg/day for women. Choline in the diet is available as free choline or is bound as esters such as phosphocholine, glycerophosphocholine, sphingomyelin, or phosphatidylcholine.
Inositol and choline are subfractions of phosphoglyceride. Inositol and choline are subfractions of phosphoglyceride, when combined with sphingosine and fatty acid make sphingomyelin. These two molecules comprise the essential building blocks that form the bilayers of cell membranes.
National Academy of Sciences recognizes choline as an essential nutrient.
Sources: Soybeans, liver, oatmeal, cabbage, cauliflower, egg yolks, meat, milk, legumes, whole grain cereals and some vegetables
Synergist: Vitamin A, B-Complex, B-12, Folic Acid, Inositol
Signs or Symptoms of a Deficiency: GABA, niacinamide and inositol, prevent anxiety and stress related messages from reaching the motor centers of the brain by occupying the receptor sites.
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