Thioctic Acid, Alpha-lipoic acid
Deficiency- lack of growth in protozoa and bacteria.
Optimal intake- 300-600 mg
Discussion- A-Lipoic Acid has been used recently in Diabetes treatment. •
Also known as thioctic acid, alpha-lipoic acid is a naturally occurring compound that is synthesized by plants and animals,
including humans. Lipoic acid is a ''non-vitamin" nutrient that is essential to life. It is not classified as a vitamin because it is produced in the body. It is generally involved in oxidative decarboxylations of keto acids and is presented as a growth factor for some organisms. Alpha-lipoic acid is a disulfide compound that is a cofactor in vital energy-producing reactions in the body. The body appears to be able to manufacture enough alpha-lipoic acid for its metabolic functions, but the excess levels provided by supplements allow alpha-lipoic acid to circulate in a free state.
Although alpha lipoic acid is involved in cellular energy production, its chief role as a dietary supplement may be as a powerful antioxidant. Unlike other antioxidants, lipoic acid is both fat and water-soluble and is easily absorbed and transported across cell membranes. This unique quality offers protection against free radicals both inside and outside the cell while other antioxidants only provide extracellular protection. Lipoic acid has the ability to regenerate other antioxidants like vitamin E, vitamin C and GSH for further use after they have eradicated free radicals.
Technicals: Lipoic acid is an antioxidant, which means it neutralizes naturally occurring, but harmful, chemicals known as free radicals. Free radicals are high-energy, very unstable chemical substances and are known to damage the cells, DNA, proteins and essential fats in the body. Alpha-lipoic acid boosts glutathione levels in cells, has potent antioxidant action in almost all the tissues of the body, and is a co-factor for some of the key enzymes involved in generating energy from food and oxygen in mitochondria.
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